Founding Backend Engineer

Founding Backend Engineer at Novaflow — San Francisco, CA, US

  • Company: Novaflow
  • Location: San Francisco, CA, US
  • Employment type: FULL_TIME
  • Salary: USD 150000–250000 / year
  • Posted: 2026-07-17

About this role

About Novaflow

Novaflow is the AI data analyst for biology labs. Analytics is the bottleneck for scientific discovery. Biologists have to outsource analysis to expensive bioinformaticians or core services and wait weeks or months for results. We're solving this by putting analysis directly back into the hands of researchers, allowing them to go from raw data to publication-ready insights and visualizations in days instead of months. We're well-funded, growing extremely fast, and backed by leading investors including Y Combinator and BioRender.

About the Role

We're hiring a Founding Backend Engineer to build the infrastructure and services that make the whole platform work. APIs, cloud infrastructure, databases, data pipelines for moving large genomics datasets through the system. You'll make the architecture decisions that determine how this thing scales.

This is a high-agency, high-ownership role. You'll work directly with the founders on system design and have a major say in how we build our engineering team and processes. Biology background is not required. You just need to be a strong engineer who can build reliable systems.

This role is in-person at our San Francisco office. The founding team works side by side every day to make fast decisions and ship.

What You'll Work On

Build and maintain APIs and backend services in Python, Go, or similar

Set up and manage cloud infrastructure on AWS or GCP

Work with SQL and NoSQL databases, optimize queries, design data models

Build data pipelines and integrations with third-party services

Manage data infrastructure (storage, compute) for large-scale workloads

Set up CI/CD pipelines, monitoring, and observability

Help build the engineering team and establish how we work

Requirements

Bachelor's or Master's in Computer Science, Engineering, or related field (or equivalent experience)

2+ years building and running backend services in production

Strong with cloud platforms, Terraform, Docker, and Kubernetes

Deep SQL knowledge and data modeling experience

Proficient in Python and Node.js for APIs and services

Experience with microservices, service-to-service communication, and API design

Familiar with CI/CD, monitoring, and keeping production systems healthy

Good communicator who can explain technical decisions clearly

Nice to Have

Experience with computational biology or scientific computing workloads

Go experience

Experience with event-driven architectures or message queues (Kafka, RabbitMQ, SQS)

Startup background

Previous startup experience (prior experience either working for or founding a startup)

Why Join Us?

Competitive salary and meaningful equity as a founding team member

401(k) with company match

Unlimited PTO + federal holidays

Monthly health and wellness stipend

Meals covered when you're in the office (lunch daily, dinner when you're working late)

Team offsites and company events

If you're curious about being a founder one day, this is your front-row seat. You'll work side by side with the founders and have full visibility into product strategy, customer conversations, and fundraising as we scale.

Apply for this position