Founding Bioinformatics Engineer

Founding Bioinformatics Engineer at Novaflow — San Francisco, CA, US

  • Company: Novaflow
  • Location: San Francisco, CA, US
  • Employment type: FULL_TIME
  • Salary: USD 100000–150000 / year
  • Posted: 2026-07-17

About this role

About Novaflow

Novaflow is the AI data analyst for biology labs. Analytics is the bottleneck for scientific discovery. Biologists have to outsource analysis to expensive bioinformaticians or core services and wait weeks or months for results. We're solving this by putting analysis directly back into the hands of researchers, allowing them to go from raw data to publication-ready insights and visualizations in days instead of months. We're well-funded, growing extremely fast, and backed by leading investors including Y Combinator and BioRender.

About the Role

We're hiring a Founding Bioinformatics Engineer to own the analysis pipelines behind our platform. You'll build the workflows that take raw sequencing data and turn it into something a biologist can actually use, make sure the science is right, and figure out how to do all of it at scale on cloud infrastructure.

This is a high-agency, high-ownership role. You'll work directly with the founders, have real input on what we build and how we build it, and be expected to drive things forward on your own.

This role is in-person at our San Francisco office. The founding team works side by side every day to make fast decisions and ship.

What You'll Work On

Build and maintain bioinformatics pipelines for genomics, transcriptomics, and other -omics data

Write clean, reproducible analysis code in Python and/or R

Set up and manage cloud infrastructure (AWS or GCP) for large-scale compute workloads

Integrate existing bioinformatics tools, databases, and data sources into the platform

Validate pipeline outputs against published methodologies and real scientific standards

Work with academic labs, tool providers, and data partners to expand what the platform can do

Help decide what we build next based on what researchers actually need

Requirements

Bachelor's or Master's in Computational Biology, Bioinformatics, Biomedical Engineering, or a related field (PhD is a plus)

2+ years building bioinformatics pipelines or computational biology workflows

Strong in Python and/or R

Know your way around bioinformatics file formats (FASTQ, BAM, VCF, HDF5, etc.)

Experience running workloads on AWS or GCP

Comfortable in Linux/Unix command-line environments

Solid understanding of molecular biology (genomics, gene expression, variant calling)

Good communicator who can work across biology and engineering

Nice to Have

Experience with Nextflow, Snakemake, or similar workflow managers

Docker experience

Familiarity with LLMs or AI/ML tools

Experience across multiple biomedical domains

Startup or biotech/pharma background

Previous startup experience (prior experience either working for or founding a startup)

Why Join Us?

Competitive salary and meaningful equity as a founding team member

401(k) with company match

Unlimited PTO + federal holidays

Monthly health and wellness stipend

Meals covered when you're in the office (lunch daily, dinner when you're working late)

Team offsites and company events

If you're curious about being a founder one day, this is your front-row seat. You'll work side by side with the founders and have full visibility into product strategy, customer conversations, and fundraising as we scale.

Apply for this position